RASOnD - A comprehensive resource and search tool for RAS superfamily oncogenes from various species
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چکیده
منابع مشابه
Oncogenes in Human Cancer: A Review ras
Mutations in codon 12, 13, or 61 of one of the three ras genes, 11-ra.v, k-ra.v, and N-ra.v,convert these genes into active oncogenes. Rapid assays for the detection of these point mutations have been developed recently and used to investigate the role mutated ras genes play in the pathogenesis of human tumors. It appeared that ras gene mutations can be found in a variety of tumor types, althou...
متن کاملras Oncogenes in Human Cancer: A Review1
Mutations in codon 12, 13, or 61 of one of the three ras genes, 11-ra.v, k-ra.v, and N-ra.v,convert these genes into active oncogenes. Rapid assays for the detection of these point mutations have been developed recently and used to investigate the role mutated ras genes play in the pathogenesis of human tumors. It appeared that ras gene mutations can be found in a variety of tumor types, althou...
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this thesis is based upon the works of samuel beckett. one of the greatest writers of contemporary literature. here, i have tried to focus on one of the main themes in becketts works: the search for the real "me" or the real self, which is not only a problem to be solved for beckett man but also for each of us. i have tried to show becketts techniques in approaching this unattainable goal, base...
15 صفحه اولTransforming ras oncogenes and multistage carcinogenesis.
Transforming ras oncogenes and multistage carcinogenesis Few topics have caught the imagination of both clinicians and scientists in the field of cancer research as readily as the recent studies on oncogenes and their role in tumour development. The first identification of transforming genes in human tumours (Der et al., 1982; Parada et al., 1982; Santos et al., 1982) was greeted in certain cir...
متن کاملThe Ras superfamily at a glance.
The Ras superfamily of small guanosine triphosphatases (GTPases) comprise over 150 human members (Table S1 in supplementary material), with evolutionarily conserved orthologs found in Drosophila, C. elegans, S. cerevisiae, S. pombe, Dictyostelium and plants (Colicelli, 2004). The Ras oncogene proteins are the founding members of this family, which is divided into five major branches on the basi...
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ژورنال
عنوان ژورنال: BMC Genomics
سال: 2011
ISSN: 1471-2164
DOI: 10.1186/1471-2164-12-341